Domio – Spiromesifen 22.9% SC

Domio is an insecticide manufactured by MaxxGro Agrology Limited, containing Spiromesifen 22.9% as a suspension concentrate (SC) formulation. It is used for the control of whitefly and mite in cotton. Spiromesifen is a tetronic-acid-derivative insecticide/acaricide that disrupts lipid biosynthesis in target pests.

Spiromesifen 22.9% SC is also registered for use in brinjal, apple and chilli against mites. As a suspension concentrate, Domio is diluted in water before spray application, and should be used strictly as per the crop, pest, dose and timing recommendations on the approved product label.

CROP Common Name of Pest Dosage / Acre Dilution in Water (L/acre) Waiting Period (Days)
Brinjal Red spider mite 38.9 g A.I.

162 ml formulation

202 5
Cotton Whitefly & mite 58.3 g A.I.

243 ml formulation

202 10
Apple European red mite & Red spider mite 29.1 g (0.03%) A.I.

121 ml formulation

405 30
Chilli Chilli yellow mite 38.9 g A.I.

162 ml formulation

202-304 7
Tea Red spider mite 38.9 g A.I.

162 ml formulation

162 7
Okra (Bhindi) Red spider mite 38.9-48.6 g A.I.

162-202 ml formulation

202 3
Tomato Whiteflies & Mites 60.7 g A.I.

253 ml formulation

202 3
  • Contains Spiromesifen 22.9% as the active ingredient
  • Formulated as a Suspension Concentrate (SC)
  • Insecticide/acaricide category product for pest management
  • Registered use in cotton, among other listed crops
  • Targets whitefly and mite
  • Lipid biosynthesis-inhibiting mode of action

Spiromesifen is a tetronic acid derivative that inhibits acetyl-CoA carboxylase, an enzyme required for lipid biosynthesis in target pests. This disrupts normal growth and development, particularly affecting the reproduction and development of whiteflies and mites. Spiromesifen is classified under IRAC Group 23 (inhibitors of acetyl-CoA carboxylase).

Domio (Spiromesifen 22.9% SC) is diluted in the recommended volume of water and applied as a foliar spray in cotton, using standard knapsack or boom sprayers, following the approved product label.

  • Use strictly as per the directions on the approved product label
  • Wear appropriate personal protective equipment during mixing and spraying
  • Avoid spray drift onto sensitive or non-target crops
  • Keep out of reach of children and away from food, feed, and water sources
  • Store in a cool, dry place in original packaging

Frequently Asked Questions

What is Spiromesifen 22.9% SC?
Spiromesifen 22.9% SC is a suspension concentrate insecticide/acaricide formulation containing 22.9% Spiromesifen as the active ingredient, used for whitefly and mite control in crops such as cotton.
What is Domio?
Domio is MaxxGro Agrology Limited’s branded insecticide product containing Spiromesifen 22.9% SC.
What is Domio used for?
Domio is used to control whitefly and mite in cotton, and is also registered for mites in brinjal, apple and chilli.
What is the dose of Domio?
For cotton, the recommended dose is approximately 243 ml of product per acre (600 ml/ha), diluted in 200 L of water per acre (500 L/ha), as per the approved label.
How does Spiromesifen work?
Spiromesifen inhibits acetyl-CoA carboxylase, disrupting lipid biosynthesis in whiteflies and mites, and is classified under IRAC Group 23.

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